Post transcriptional reactions have been implicated in a number of clinical conditions (e.g. lupus, and rheumatoid arthritis), and regulatory mechanisms are the target of potential therapeutic strategies. This book provides a comprehensive overview of the various modes of gene regulation that exist post transcriptionally.
Taal / Language : English
Partial table of contents:
RNA Structure (E. Puglisi & J. Puglisi).
Transcription and Transcriptional Control: An Overview (I. Olave, et al.).
Constitutive and Alternative mRNA Splicing (S. Bernstein & D. Hodges).
mRNA Polyadenylation: Functional Implications (E. Baker).
RNA Export from the Nucleus (L. Maquat).
The Intracellular mRNA Sorting System: Postal Codes, Zip Codes, Mail Bags and Mail Boxes (O. Steward & R. Singer).
The Fundamentals of Translation Initiation (H. Huang & T. Donahue).
Mechanisms of mRNA Turnover in Eukaryotic Cells (S. Tharun & R. Parker).
Control of mRNA Decay in Plants (A. van Hoof & P. Green).
mRNA Metabolism and Cancer (M. Korth & M. Katze).
Translational Regulation in Animal Virus Infected Cells (R. Schneider).
RNA Decay by the Interferon Regulated 2 5A System as a Host Defense Against Viruses (R. Silverman & N. Cirino).
Control of mRNA Stability During Herpes Simplex Virus Infection (G. Read).
Regulation of mRNA Expression in HIV 1 and Other Retroviruses (B. Felber).
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