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Nederlands Buitenlands   Alles  Titel  Auteur  ISBN        
Levende natuur
Biologie algemeen

Michael D. Greenberg

Radical and Radical Ion Reactivity in Nucleic Acid Chemistry

€ 161.30

The chemistry and biochemistry of reactive intermediates is central to modern mechanistic and quantitative understanding of organic chemistry and biochemistry. It underlies a significant portion of modern synthetic chemistry and is integral to a molecular view of biological chemistry.


Taal / Language : English

Inhoudsopgave:
Preface to Series.

Introduction.

Contributors.

1. Theoretical Modeling of Radiation Induced DNA Damage (Anil Kumar and Michael D. Sevilla).

2. Radical Reaction Pathways Initiated by Direct Energy Deposition in DNA by Ionizing Radiation (William A. Bernhard).

3. Chemical Reactions of the Radical Cations of Nucleobases in Isolated and Cellular DNA. Formation of Single Base Lesions (Jean Cadet, Thierry Douki, Didier Gasparutto, Jean Luc Ravanat, and J. Richard Wagner).

4. Reactivity of Nucleic Acid Sugar Radicals (Chryssostomos Chatgilialoglu).

5. Pyrimidine Nucleobase Radical Reactivity (Marc M. Greenberg).

6. Reactivity of 5 Halopyrimidines in Nucleic Acids (Ryu Tashiro and Hiroshi Sugiyama).

7. Kinetics of Long Range Oxidative Electron Transfer Through DNA (Kiyohiko Kawai and Tetsuro Majima).

8. Radical Intermediates During Reductive Electron Transfer Through DNA (Reji Varghese and Hans Achim Wagenknecht).

9. Low Energy Electron Interaction with DNA: Bond Dissociation and Formation of Transient Anions, Radicals, and Radical Anions (Léon Sanche).

10. Electronic Affinic Radiosensitizers (Peter Wardman).

11. Reactions of Reactive Nitrogen Species and Carbonate Radical Anions with DNA (Vladimir Shafirovich, Conor Crean, and Nicholas E. Geacintov).

12. Principles and Applications of Electrochemical Oxidation of Nucleic Acids (H. Holden Thorp and Julie M. Sullivan).

13. DNA Damage Due to Diradical Generating Cyclizations (Sean M. Kerwin).

14. DNA Damage by Phenoxyl Radicals (Richard A. Manderville).

Index.
Extra informatie: 
Hardback
472 pagina's
Januari 2009
771 gram
241 x 159 x 25 mm
John Wiley & Sons Inc us

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